GSK 690
CAS No. 2101305-84-2
GSK 690 ( GSK690 )
Catalog No. M13334 CAS No. 2101305-84-2
GSK 690 is an irreversible, mechanism based inhibitor of lysine specific demethylase 1 (LSD1) with IC50 of 77 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 873 | Get Quote |
|
50MG | 1782 | Get Quote |
|
100MG | 2250 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameGSK 690
-
NoteResearch use only, not for human use.
-
Brief DescriptionGSK 690 is an irreversible, mechanism based inhibitor of lysine specific demethylase 1 (LSD1) with IC50 of 77 uM.
-
DescriptionGSK 690 is an irreversible, mechanism based inhibitor of lysine specific demethylase 1 (LSD1) with IC50 of 77 uM.
-
SynonymsGSK690
-
PathwayChromatin/Epigenetic
-
TargetHistone Demethylase
-
RecptorHistone Demethylase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2101305-84-2
-
Formula Weight369.47
-
Molecular FormulaC24H23N3O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESN#CC1=CC=C(C2=CC(OC[C@H]3CNCC3)=CN=C2C4=CC=C(C)C=C4)C=C1
-
Chemical Name(R)-4-[5-(Pyrrolidin-3-ylmethoxy)-2-p-tolyl-pyridin-3-yl]-benzonitrile
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Mould DP, et al. J Med Chem. 2017 Sep 11. doi: 10.1021/acs.jmedchem.7b00462.
2. Mould DP, et al. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4755-4759.
3. McGrath JP, et al. Cancer Res. 2016 Apr 1;76(7):1975-88.
2. Mould DP, et al. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4755-4759.
3. McGrath JP, et al. Cancer Res. 2016 Apr 1;76(7):1975-88.
molnova catalog
related products
-
KDOAM-25
KDOAM-25 (KDM5 inhibitor KDOAM 25) is a potent, selective KDM5 sub-family(JARID1) inhibitor.
-
Dot1L-IN-4
Dot1L-IN-4 is a potent disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor.
-
ORY-1001 dihydrochlo...
ORY-1001 dihydrochloride (RG-6016, Ladademstat) is a highly potent, selective inhibitor of lysine-specific demethylase KDM1A (LSD1) with IC50 of 18 nM.